Are Anavar gains permanent and how much muscle mass will you keep after you stop your cycle?
Anavar is a brand name for the oral anabolic steroid Oxandrolone.
Anavar has been shown to be useful in treating women with osteoporosis, patients with wasting conditions related to HIV/AIDS, and in healing burns and other wounds.
It can be used to counteract weight loss after major surgery, long-term illness and severe trauma.
It is also popular among athletes for preserving lean muscle tissue while reducing body fat and for encouraging linear growth.
Anavar muscle gains can be made permanent with the right post-cycle therapy and an effective cycle routine. Click here to buy legal Anavar online, without a prescription.
Anavar is only mildly hepatotoxic as compared with other anabolic steroids, which means that while it can cause stress to the liver, it has less tendency to cause liver damage than similar steroids.
It is sometimes used by professional athletes to counteract breakdown of proteins that can be caused by extended use of corticosteroids and to alleviate bone pain from osteoporosis.
Anavar is classified as a Schedule III controlled substance in accordance with the Anabolic Steroids Control Act of 1990.
Schedule III controlled substances are those that have an accepted medical use and limited potential for abuse.
Anavar does not aromatize, or convert to estrogen, like other steroids tend to do, so many of the side effects that are common with other steroids are rare with Anavar.
Women who are pregnant or breastfeeding should avoid Anavar, as should children, those who are allergic to any ingredients, and those receiving treatment for certain cancers, high blood pressure, stroke or liver damage.
Anavar tablets are made up of the active ingredient Oxandrolone combined with inactive ingredients including corn starch, lactose, magnesium stearate, and hydroxypropyl methylcellulose.
Anavar has a half-life of about nine hours and is detectable in drug tests for as long as four weeks after use.
The typical daily dose of Anavar is 20-100 mg for men and 2.5-20 mg for women.
For maximum muscle gains, it can be stacked with other performance enhancing drugs and anabolic steroids like HGH, Proviron, Primobolan, Halotestin, Equipoise, and Winstrol.
When an athlete is attempting to lose weight in preparation for an even, Anavar is one of the most popular drugs for cutting.
It is highly effective at encouraging fat loss while protecting lean muscle mass.
This means you can use it to protect your gains from other mass-building steroids that are better suited for bulking in the off-season.
Anavar is not associated with increases in estrogen levels, so does not cause many of the side effects that some other steroids can cause.
It has been used to help promote healing of wounds and burns and is recommended by doctors to combat wasting conditions related to HIV/AIDS and to alleviate bone pain in women suffering from osteoporosis.
Anavar is commonly stacked with other performance enhancing drugs such as HGH, Winstrol, Primobolan, Equipoise, Proviron or Halotestin.
Female physiology is far more sensitive than male physiology, so the recommended dose for men is much higher than that recommended for women.
Oxandrolone raises levels of both free and protein-bound cortisol, probably because of its tendency to act as a cortisol receptor antagonist.
Oxandrolone also tends to dramatically lower thyroid binding globulin concentrations, which leads to elevated thyroxine-binding prealbumin and increased T3 uptake and creatine update.
This tends to confirm the idea that oxandrolone is helpful during cutting cycles, whether on its own or as part of a stack.
In another, participants saw an average of four pounds decrease in fat and an average of seven pounds increase in lean muscle mass over 12 weeks at a twice daily dose of 10 mg of oxandrolone.
Other evidence exists to suggest that oxandrolone boosts ketogenesis. These kinds of Anavar gains are what make it so popular today as one of the most widely purchased steroids.
But are the muscle gains permanent or is all that mass really just due to water retention?
It is true that there is some water retention involved, but studies have shown that some of the gains are permanent and will last after you end your cycle.
Anavar is derived from dihydrotestosterone (DHT) and was first manufactured in 1964 by the pharmaceutical company Searle.
Anavar does not tend to bind with androgen receptor, but its relatively long half life makes it moderately potent.
The A-ring has an oxygen atom embedded at the 2-position and forms a structure known as a heterocycle.
Because Anavar is DHT derived, and because of the heterocycle, oxandrolone does not aromatize to convert to estrogenic metabolites.
Because Oxandrolone is already 5-alpha reduced, it cannot be further reduced by 5-alpha reductase.
The existence of the oxygen in that 2-position on the A-ring means that the steroid is not destroyed by 3-alpha hydroxysteroid dehydrogenase (3HSD) in skeletal muscle.
3HSD is an enzyme that reacts to DHT and denatures it. Anavar does not attach to sex hormone binding globulin (SHBG) so that all of the Anavar in the blood stream is active and potent.
Androgenic anabolic steroids are known to lower levels of SHBG in the body, which often results in higher levels of estrogen, which in turn leads to certain side effects.
Anavar strength and muscle gains may not do this to the same degree as many of its counterparts, but it still has this capability.
For many years, there was a misconception that oxandrolone could not convert to estrogen and would not hinder testosterone production.
It is now understood that androgen can also lower luteinizing hormone in the same way as estrogens. It is this process that leads to a lowering of the body’s ability to produce testosterone.
A study carried out by Sheffield-Moore, et al. showed that it only took 15 mg per day over 5 days to lower testosterone levels in healthy young men.
There is no evidence to suggest that oxandrolone reacts with progesterone receptors, but it may have anti-cortisol effects.
Oxandrolone gains raises nitrogen levels not only as a result of the anabolic activation of androgen receptors, but also by antagonism of cortisol’s catabolic effects.
Cortisol is a well-known stress hormone. Cortisol works by breaking down muscle tissue to provide glucose for energy.
Other supplements that block cortisol include phosphatidylserine.
One of the common side effects of anabolic steroids in women is virilization, which refers to the appearance of masculine characteristics, such as body hair and deepening of the voice.
While Anavar can cause these side effects, they are rare, especially when the drug is used responsibly and at recommended doses, so most female athletes can use Anavar for gains without worry.
Though side effects of Anavar are rare when used responsibly, abuse of the drug can lead to increases in certain liver enzymes as well as atrophying testicles, impotence, chronic priapism, decreased sperm count or male infertility, irritable bladder, impaired function of the testicles, and testicular pain.
Though oxandrolone is C-17 alpha alkylated, which makes it able to pass through the liver without denaturing, studies show it to be fairly mild on the liver, though as doses go up, risk of harm to the liver also increases.
Oxandrolone is considered to be weak, and for that reason is often used by female athletes.
Make no mistake, Oxandrolone may be mild, but it is still capable of producing such androgenic side effects as hair loss, body and facial hair, deeper voice, acne and enlargement of the clitoris.
It takes particularly high doses to realize significant gains in size, especially for male users, though increases in strength can be achieved at lower doses.
Doses of 20-50 and as much as 100 mg per day are typical among male users.
Using Anavar for gains in muscle mass is significantly more expensive than other anabolic steroids, and the cost tends to be quite prohibitive, especially at the high doses needed by male athletes.
It also tends to be less readily available than certain other steroids.